One of the great things about roleplaying games is that just about anything can be used as inspiration for a campaign, setting or encounter. Homebrew Dungeons and Dragons campaigns truly are "Products of Your Imagination(TM)."
For me, music is a powerful source of gaming inspiration. Some two decades ago, I used "King Of Pain," by The Police, as the basis for an encounter. The setting: five seated statues, not specifically identified, but representing the Gods of War, Pain, Plenty, Peace, and Death.
Behind the statues, were various paintings; clues to the encounter, and all images from the Police song. Moving the Statue of the God of Pain would unlock a secret door: moving any of the other statues would jam the secret door mechanism.
Obviously, this tested player skill, not character skill. But I had two huge Police fans at the table, so the test was entirely fair.